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ETF analysis

Direxion Daily S&P Biotech Bull 3X ETF (LABU) holdings & weights

Per-holding contribution · concentration · sector skew — a deep read

Leverage/Inverse 3xUS-listedAs of 2026-10-19
IndexS&P Biotechnology Select Industry
Annual fee0.96%
Net assets$575M
InceptionMay 28, 2015

Fund overview

This is a US-listed ETF from Direxion. It tracks the S&P Biotechnology Select Industry. Key facts — expense ratio 0.96%; net assets about $575M; inception May 28, 2015. Its 1-year return is +107.2%.

Index tracked
S&P Biotechnology Select Industry
Provider
Direxion
Expense ratio
0.96%
Net assets (AUM)
$575M
Inception
May 28, 2015
1-year return
+107.2%
Holdings
173
52-week range
$108.9–$341.93
Fund details

Fund overview

This is a US-listed ETF from Direxion. It tracks the S&P Biotechnology Select Industry. Key facts — expense ratio 0.96%; net assets about $575M; inception May 28, 2015. Its 1-year return is +107.2%.

Index tracked
S&P Biotechnology Select Industry
Provider
Direxion
Expense ratio
0.96%
Net assets (AUM)
$575M
Inception
May 28, 2015
1-year return
+107.2%
Holdings
173
52-week range
$108.9–$341.93

157 identified stocks · net exposure / NAV 299.89%. Display weights are normalized to 100%; calculations retain original exposures without an additional leverage multiplier. Underlying allocation is estimated using XBI (2026-10-16). Cash and unallocated contracts are excluded from stock attribution.

Weight and calculation basis

157 identified stocks · net exposure / NAV 299.89%. Display weights are normalized to 100%; calculations retain original exposures without an additional leverage multiplier. Underlying allocation is estimated using XBI (2026-10-16). Cash and unallocated contracts are excluded from stock attribution.

—
Holdings not priced
18.1%
Top-10 weight
112
Concentration HHI (Low)
Health Care
Top sector

We have this ETF's holdings, but the prices for those particular listings are outside our quote coverage (currently Korea- and US-listed securities). So today's contribution and return are not computed — showing 0% would claim it did not move, which is a different statement. The holdings and weights below follow the calculation basis above.

Today's summary

Its top 10 holdings make up about 18.1% of the fund. The concentration index (HHI) is 112 — Low — evenly diversified, and the largest sector is Health Care (99%). The higher the concentration, the more one stock or sector drives the whole ETF's return.

Structural health

A five-axis read on how this fund is built. It is not a return forecast or a recommendation, and a low score does not mean a bad fund — leveraged products score low by design. Each axis shows the figure behind it.

37/ 100
DHigh-risk structure
DiversificationHHI 112100

Concentration is below 1,500 (112), so no single holding dominates.

Sector balanceHealth Care 99%0

Health Care alone is 99%. This is effectively a bet on that one industry — if the sector falls, diversification will not help.

Cost0.96%/yr21

0.96% a year is on the high side — about 9.6% over a decade, so it needs a reason to earn that.

Fund size$575M41

Net assets of $575M — liquid enough to trade, and unlikely to be wound down.

Structural simplicityLeveraged 3x10

A 3x leveraged fund. It resets exposure daily, so over more than a few days the result drifts from "index move × 3". Built for short holds.

Concentration and diversification

Structural health

A five-axis read on how this fund is built. It is not a return forecast or a recommendation, and a low score does not mean a bad fund — leveraged products score low by design. Each axis shows the figure behind it.

37/ 100
DHigh-risk structure
DiversificationHHI 112100

Concentration is below 1,500 (112), so no single holding dominates.

Sector balanceHealth Care 99%0

Health Care alone is 99%. This is effectively a bet on that one industry — if the sector falls, diversification will not help.

Cost0.96%/yr21

0.96% a year is on the high side — about 9.6% over a decade, so it needs a reason to earn that.

Fund size$575M41

Net assets of $575M — liquid enough to trade, and unlikely to be wound down.

Structural simplicityLeveraged 3x10

A 3x leveraged fund. It resets exposure daily, so over more than a few days the result drifts from "index move × 3". Built for short holds.

Top 20 holdings

Weights are normalized to 100% of absolute exposures across analysed positions, including positions outside this top list. Cash, collateral and unverified assets are excluded. Contributions retain original signed NAV exposures; leverage is not applied twice.

Normalized to 100% of analysed positions

Weights are normalized to 100% of absolute exposures across analysed positions, including positions outside this top list. Cash, collateral and unverified assets are excluded. Contributions retain original signed NAV exposures; leverage is not applied twice.

Tile size = weight, colour = the day's return (deeper = larger). Covers the top 30 holdings, 138.9% of the fund. Labels are dropped where a tile is too small; hover any tile for its name and figures.
#HoldingWeight
1MODERNAMRNA2.53%
2NATERANTRA1.87%
3ABBVIEABBV1.79%
4HALOZYME THERAPEUTICSHALO1.78%
5AMGENAMGN1.74%
6BIOGENBIIB1.74%
7GILEAD SCIENCESGILD1.69%
8EXELIXISEXEL1.68%
9TWIST BIOSCIENCETWST1.66%
10UNITED THERAPEUTICSUTHR1.65%
11IOVANCE BIOTHERAPEUTICSIOVA1.63%
12TG THERAPEUTICSTGTX1.55%
13REGENERON PHARMACEUTICALSREGN1.54%
14VERTEX PHARMACEUTICALSVRTX1.51%
15SPYRE THERAPEUTICSSYRE1.45%
16KRYSTAL BIOTECHKRYS1.43%
17ALKERMESALKS1.43%
18CRISPR THERAPEUTICSCRSP1.42%
19ALNYLAM PHARMACEUTICALSALNY1.41%
20INCYTEINCY1.41%

Holdings below 0.5% or outside the top list are folded into “Others” and omitted above.

Where the weight sits — sector mix

Listed equity weights summed by sector and normalized to 100%. Each band is one sector's share.

Health Care99.4%
Financials0.6%
Industry breakdown
Biotechnology: Pharmaceutical Preparations53.7%
Biotechnology: Biological Products (No Diagnostic Substances)35.5%
Medical Specialities5.8%
Biotechnology: In Vitro & In Vivo Diagnostic Substances2.5%
Biotechnology: Commercial Physical & Biological Resarch1.9%
Finance: Consumer Services0.6%
Medical/Dental Instruments0.1%
Concentration at a glanceHHI 112well spread
spread1,0001,8002,500concentrated

HHI sums the squared weights. The more it leans on a few names, the higher it goes — and the more the whole ETF moves with them.

Leverage / inverse caveat

This fund tracks its index at 3x.

That 3x applies to a **single day**. Held longer, the daily reset makes the period return drift from 3x the index: if the index chops up and down and returns to where it started, this fund is still down. That is volatility decay.

It bites hardest in sideways markets and compounds with holding time. These are built for short directional trades.

How concentrated is it

Concentration (HHI) is low at 112, with the top 10 holdings at just 18.1% of equity weight. No single name can dominate the fund.

Good for damping single-stock risk — and equally, a big winner inside gets diluted.

HHI squares each weight and sums them: 10,000 means one stock is everything, and the more evenly spread the holdings, the closer it falls to zero.

Where the sector weight sits

By sector, Health Care alone is 99% — whatever the fund is called, this is a bet on that industry.

Bad news for the sector moves the whole fund. Worth checking against anything else you hold in the same space.

Weights above sum the individually listed equities and normalize that equity total to 100%.

How much it overlaps others

Even its closest peer, MIDU, overlaps only 9% (11 shared names).

Funds filed under the same label can hold quite different companies, so pairing this one with another may genuinely spread risk.

What it is made of

The fund holds 173 positions in total; this page lists the largest 157 and folds the rest into "Others".

The expense ratio is 0.96% a year, which is not cheap. Fees come out of returns every year you hold, so it is worth checking whether the same index is available for less.

This page is not investment advice. Investment decisions and responsibility are your own.

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